AZ5104 Drip Tip

AZ5104 Drip TipAZ5104, the demethylated metabolite of AZD 9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Phase 1.

no activiy against a panel of 52 diverse protein kinases

Torcetrapib is a CETP inhibitor with IC50 of 37 nM

7 nM and 38 nM

used in the form of Lapatinib Ditosylate

As an endogenous compound

Ufenamate is an anthranilic acid derivative with anti-inflammatory activity

(-)-MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30

copy and archive data

and TrkA/B

and also inhibits c-Kit

stability and repeatability over time

Thiazovivin is a novel ROCK inhibitor with IC50 of 0